Australia beat Wales 36-28 on Saturday to hand the Welsh their ninth consecutive loss.
The Wallabies won the opening match over Wales 25-16 in Sydney.
Winger Filipo Daugunu scored Australia’s first try and his first of two on the night sparked by a Andrew Kellaway chip and chase in the seventh minute.
Jake Gordon scored the second in the 25th minute to help give the Wallabies an early 17-0 lead in pouring rain at AAMI Stadium.
But Wales hooker and captain Dewi Lake scored two tries to pull Wales back to 23-14 at halftime.
Lake’s second try came with Australia lock Lukhan Salakaia-Loto sent off for 10 minutes after receiving a yellow card.
Wales closed to 23-21 when Liam Williams scored seven minutes into the second half – the first time the 91 Test veteran had scored a try against Australia.
Replacement prop Allan Alaalatoa gave Australia a 28-21 lead with an unconverted try in the 54th minute.
Daugunu’s second try came when it appeared the two teams were exchanging penalties, but Williams jumped up to keep the ball in play and sent it instead into the path of Daugunu, who ran in for an easy try.
Wales winger Rio Dyer scored with 10 minutes left to make it 33-28 but a late penalty clinched the win for the Wallabies.
Wales has not beaten the Wallabies in 14 Tests in Australia since 1969.
Worse yet, the Welsh are closing in on matching their worstever streak of 10 consecutive losses.
The Welsh losing streak began last year in the Rugby World Cup quarter-finals, continued with five losses in the Six Nations and was extended to June when Wales lost to World Cup champions South Africa in London.
Joe Schmidt, who took over as Australia coach after Eddie Jones’ tumultuous tenure ended in January, is now perfect after two matches in charge.